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Pre-Lab Questions
Assumptions:
· There are approximately 3,000,000,000 base pairs in the mammalian genome (genes constitute only a portion of this total).
· There are approximately 10,000 genes in the mammalian genome.
· A single gene averages 10,000 base pairs in size.
· Only 1 out of 3 mutations that occur in a gene result in a change to the protein structure.
In the mammalian genome:
1. How many total base-pairs are in all the mammalian genes?
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2. What proportion (%) of the total genome does this represent?
3. What is the probability that a random mutation will occur in any given gene?
4. What is the probability that a random mutation will change the structure of a protein?
Note: In the following experiments on gene pool, gene frequency, and genetic diversity; assume there are four alleles for color and that they are all homologous.