Non-pharmacological Intervention: referal to therapy; the first-line treatment of anxiety disorders is cognitive-behavioral therapy. Multiple research demonstrates the efficacy and effectiveness of CBT in the treatment of anxiety disorders, including PTSD, OCD, panic disorder, GAD, and social anxiety disorder. Nevertheless, combined therapy of CBT and medications presents stronger evidence of effectiveness. The patient should be referred to a rheumatologist to manage the Ankylosing Spondylitis. Collaborating with the rheumatologist and PCP is essential for efficient patient care management.