1. The PMHNP is considering prescribing a 49-year-old male clozapine (Clozaril) to treat his schizophrenia and suicidal ideations. The PMHNP is aware that which factor may impact the dose needed to effectively treat his condition:
A.
The patient smokes cigarettes.
B.
The patient has hypertension.
C.
The patient has chronic kidney disease, stage 2.
D.
The patient drinks a cup of coffee a day.